Non-League Chorley and League One Blackpool pulled off contrasting upsets on an absorbing day of Emirates FA Cup action.
Blackpool, who won the famous cup in 1952-53, made it past the third round for the second time in eight seasons by beating Sam Allardyce's West Bromwich Albion 3-2 on penalties after a 2-2 draw.
It was a miserable return to Bloomfield Road for Allardyce, who started his managerial career at the club in 1994.
The Seasiders led twice, first when Jerry Yates turned in Bez Lubala’s delivery just before the break before Semi Ajayi headed in an equaliser early in the second half.
Gary Madine curled into the bottom corner to regain the lead before Matheus Pereira converted a penalty to level again.
Chris Maxwell was the hero for Blackpool with three saves to send them through to the fourth round.
In the day’s major upset, Non-League Chorley dumped former winners Derby County out of the Emirates FA Cup in the third round.
The National League North side outfought a youthful Rams side with Connor Hall and Mike Calveley’s goals writing a unique chapter in their club’s history.
Hall, 22, nodded home to become the first player to score in each of the first three rounds of the competition proper since Roarie Deacon for Sutton United in 2016-17.
Chorley were always on the front foot and Calveley volleyed home powerfully six minutes from time to cap the historic result.
Meanwhile, Emirates FA Cup holders Arsenal scored twice in extra time to beat Newcastle 2-0 at the Emirates.
Emil Smith Rowe was the centre of the action as he saw a red card overturned by VAR and then slid a superb winner into the far corner four minutes into the second period of extra time.
Pierre-Emerick Aubameyang, who scored twice in Arsenal's FA Cup final win over Chelsea last August, added sheen to the result in the closing minutes.
Burnley needed spot-kicks to see off plucky League One MK Dons, winning the shootout 4-3 after the sides drew 1-1.
In-form Cameron Jerome put the visitors in front at Turf Moor when he headed home Stephen Walker’s left-wing cross on the half-hour mark.
MK Dons thought they had been reduced to ten men when Richard Keogh was red-carded for deliberately handling in through ball, but the decision was overturned by VAR.
Burnley spurned a host of chances but left it until the fourth minute of second-half injury time to level when Matej Vydra whipped in a free-kick.
Lasse Sorensen and Ben Gladwin missed from the spot and Phil Bardsley scored the winning penalty to see Sean Dyche’s men through.
League One Bristol Rovers came from behind twice to give Sheffield United a fright, the Premier League strugglers clinging on for a 3-2 victory.
Alfie Kilgour and Max Ehmer levelled for the Gas but they ran out of steam after right-back Jayden Bogle slotted home. It was a first win in six months in all competitions for Chris Wilder’s men.
Elsewhere, Leicester City put four past 2011 finalists Stoke City to continue their good recent FA Cup record.
The Potters posed their East Midlands visitors problems but James Justin’s superb curling effort set the tone for a dominant display.
Marc Albrighton, Ayoze Perez and Harvey Barnes got on the scoresheet to fuel hope of another cup run for the Foxes, who reached the quarter-finals in 2018 and 2020.
Everton squeaked into the fourth round with a topsy-turvy 2-1 win over Rotherham United sealed in extra time.
Carlo Ancelotti, who won the FA Cup with Chelsea in 2010, saw his side throw away an early lead before Abdoulaye Doucoure finished calmly in extra time to seal progress.
In the final action of the day, Scott McTominay's early strike sealed the win for Manchester United in their third round tie against Watford.
The Scottish international headed in Alex Telles' corner within the opening five minutes at Old Trafford to see the Red Devils progress into the fourth round.