FA Cup holders Arsenal face a trip to Manchester United in the stand-out tie of this season’s Sixth Round.
The Gunners eased past Championship leaders Middlesbrough on Sunday, while United came from 1-0 down at Preston to book their place in the last eight.
Sixth Round draw
Liverpool v Blackburn Rovers
Bradford City v Reading
Manchester United v Arsenal
Aston Villa v West Bromwich Albion
Manchester United last won The Cup in 2004.
Meanwhile, Bradford City's reward for their 2-0 win over Sunderland is a quarter final tie against Reading.
The League One outfit have shocked two Premier League opponents on their way to the last eight, Chelsea and the Black Cats, and the Royals, who saw off Derby in the last round, stand between Phil Parkinson's side and a place in the Semi-Finals.
There is a Midlands derby in store as West Bromwich Albion travel to Aston Villa, who will be under the stewardship of new boss Tim Sherwood.
The first two teams out of the hat were seven-time winners Liverpool and Blackburn Rovers, who stunned Premier League Stoke City in Round Five.
The Sixth Round draw was conducted by Three Lions boss Roy Hodgson and Brian Finney, son of the legendary former England and Preston winger Tom Finney.
The four quarter final ties will take place over the weekend of Saturday 7 March. Winning clubs will receive £360,000 from The FA prize fund.