Fixtures
| Saturday 11 September 2021 | First Round Qualifying | |||||
| Kick Off | No. | Home | Away | |||
|---|---|---|---|---|---|---|
| 21 | Avro | VS | AFC Darwen | |||
| 22 | AFC Liverpool | VS | Charnock Richard | |||
| 23 | Athersley Recreation | VS | Chadderton | |||
| 24 | Brigg Town | VS | Cammell Laird 1907 | |||
| 25 | Runcorn Town | VS | Ashton Town AFC | |||
| 27 | Burscough | VS | Hallam | |||
| 28 | New Mills | VS | Armthorpe Welfare | |||
| 29 | Bacup Borough | VS | Penistone Church | |||
| 30 | St Helens Town | VS | Cheadle Heath Nomads | |||
| 31 | West Didsbury & Chorlton AFC | VS | Nostell MW | |||
| 32 | Northwich Victoria | VS | Bury AFC | |||
| 33 | Skelmersdale United | VS | Retford | |||
| 34 | Maltby Main | VS | Glasshoughton Welfare | |||
| 35 | Swallownest | VS | Bottesford Town | |||
| 36 | FC Humber United | VS | Parkgate | |||
| 37 | Selby Town | VS | Hemsworth Miners Welfare | |||
| 38 | Winterton Rangers | VS | Macclesfield | |||
| 39 | Dronfield Town | VS | Barnton | |||
| 40 | Worsbrough Bridge Athletic | VS | Maine Road | |||
| 41 | Handsworth | VS | Golcar United | |||